Manghopir or Mangopir (Urdu: منگھوپیر) is one of the neighbourhoods of Gadap Town inKarachi, Sindh, Pakistan .

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There are several ethnic groups in Manghopir including Muhajirs, Sindhis, Punjabis,Kashmiris, Seraikis, Pakhtuns, Balochis, Memons, Bohras, Ismailis, etc. Over 99% of the population is Muslim. The population of Gadap Town is estimated to be nearly one million.

Manghopir is a rural area of Karachi, named after Sufi Pir Haji Syed Sakhi Sultan. The area has the oldest Sufi shrines in the city, hot sulphur springs that are believed to have curative powers, and many crocodiles – believed locally to be the sacred disciples of Pir Mangho.  Balochs often call this place as ‘Mangi’ or Garm-aab / Sard-aab (due to the presence of the hot & cold springs).

Pir Mangho (Sindhi and Urdu: خواجہ حسن سخی سلطان عرف منگھو پیر ) is the popular name for Sufi Pir Haji Syed Khawaja Hassan Sakhi Sultan. Legends dating to the 12th century say that Mangho was an adult convert to Islam, a Hindu dacoit caravan looter who changed under the influence of Baba Farid Ganjshakar. He was titled a Pir by Baba Farid, whose disciple he became. Pir Mangho Urs is celebrated in the Islamic month of Zil Hijjah. The settlement around his shrine has been named Manghopir and is part of Gadap Town in Karachi, Sindh, Pakistan.