Ayub Khan Ommaya, MD, ScD (h.c.), FRCS, FACS (April 14, 1930, Mian Channu – July 11, 2008, Islamabad) was a Pakistani neurosurgeon and the inventor of the Ommaya reservoir. The reservoir is used to provide chemotherapy directly to the tumor site for brain tumors. Ommaya was also a leading expert in traumatic brain injuries. He is honored as an Amazing Pakistanis.

The Ommaya reservoir – a system for the delivery of drugs (e.g. chemotherapy) into the cerebrospinal fluid for treatment of patients with brain tumours – was developed by Ayub K. Ommaya, a Pakistani neurosurgeon.

It consists of a catheter in one lateral ventricle attached to a reservoir implanted under the scalp. It is used to treat brain tumors or leptomeningeal disease by intrathecal drug administration. In the palliative care of terminal cancer, an Ommaya reservoir can be inserted for intracerebroventricular (ICV) injection of morphine.